abstract：:Although the patterns of activity produced by neocortical networks are now better understood, how these states are activated, sustained, and terminated still remains unclear. Negative feedback by the endogenous neuromodulator adenosine may potentially play an important role, as it can be released by activity and there...

journal_title：Journal of neurophysiology

authors： Wall MJ,Richardson MJ

更新日期：2015-02-01 00:00:00

abstract：:The brain's ability to integrate information from different senses is acquired only after extensive sensory experience. However, whether early life experience instantiates a general integrative capacity in multisensory neurons or one limited to the particular cross-modal stimulus combinations to which one has been exp...

journal_title：Journal of neurophysiology

authors： Xu J,Yu L,Stanford TR,Rowland BA,Stein BE

更新日期：2015-02-01 00:00:00

abstract：:Most retinal bipolar cells (BCs) transmit visual input from photoreceptors to ganglion cells using graded potentials, but some also generate calcium or sodium spikes. Sodium spikes are thought to increase temporal precision of light-evoked BC signaling; however, the role of calcium spikes in BCs is not fully understoo...

journal_title：Journal of neurophysiology

authors： Lipin MY,Vigh J

更新日期：2015-01-15 00:00:00

abstract：:Some neurons in early visual cortex are highly selective for the position of oriented edges in their receptive fields (simple cells), whereas others are largely position insensitive (complex cells). These characteristics are reflected in their sensitivity to the spatial phase of moving sine-wave gratings: simple cell ...

journal_title：Journal of neurophysiology

authors： Cloherty SL,Ibbotson MR

更新日期：2015-01-15 00:00:00

abstract：:Chronic pain after nerve injury is often accompanied by hypersensitivity to mechanical stimuli, yet whether this reflects altered input, altered processing, or both remains unclear. Spinal nerve ligation or transection results in hypersensitivity to mechanical stimuli in skin innervated by adjacent dorsal root ganglia...

journal_title：Journal of neurophysiology

authors： Boada MD,Gutierrez S,Aschenbrenner CA,Houle TT,Hayashida K,Ririe DG,Eisenach JC

更新日期：2015-01-01 00:00:00

abstract：:Studies on animals have shown that noise-induced hearing loss is followed by an increase of spontaneous firing at several stages of the central auditory system. This central hyperactivity has been suggested to underpin the perception of tinnitus. It was shown that decreasing cochlear activity can abolish the noise-ind...

journal_title：Journal of neurophysiology

authors： Noreña AJ,Mulders WH,Robertson D

更新日期：2015-01-01 00:00:00

abstract：:The exercise pressor reflex, a crucial component of the cardiovascular response under physiological and pathophysiological states, is activated via metabolic and mechanical mediators that originate from contracting muscles and stimulate group III and IV afferents. We reported previously that stimulation of mu opioid r...

journal_title：Journal of neurophysiology

authors： Hassan B,Kim JS,Farrag M,Kaufman MP,Ruiz-Velasco V

更新日期：2014-12-15 00:00:00

abstract：:Under binaural listening conditions, the detection of target signals within background masking noise is substantially improved when the interaural phase of the target differs from that of the masker. Neural correlates of this binaural masking level difference (BMLD) have been observed in the inferior colliculus and te...

journal_title：Journal of neurophysiology

authors： Hughes LE,Rowe JB,Ghosh BC,Carlyon RP,Plack CJ,Gockel HE

更新日期：2014-12-15 00:00:00

abstract：:In neuroendocrine cells, hormone release often requires a collective burst of action potentials synchronized by gap junctions. This is the case for the electrically coupled bag cell neurons in the reproductive system of the marine snail, Aplysia californica. These neuroendocrine cells are found in two clusters, and fi...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Colmers PL,Hodgson HM,Magoski NS

更新日期：2014-12-01 00:00:00

abstract：:Dopamine neurons in freely moving rats often fire behaviorally relevant high-frequency bursts, but depolarization block limits the maximum steady firing rate of dopamine neurons in vitro to ∼10 Hz. Using a reduced model that faithfully reproduces the sodium current measured in these neurons, we show that adding an add...

journal_title：Journal of neurophysiology

authors： Qian K,Yu N,Tucker KR,Levitan ES,Canavier CC

更新日期：2014-12-01 00:00:00

abstract：:Human subjects chose between two color-coded reach targets using multicolored checkerboard-like decision cues (DCs) that presented variable amounts of conflicting sensory evidence supporting both target choices. Different DCs contained different numbers of small squares of the two target colors. The most ambiguous DCs...

journal_title：Journal of neurophysiology

authors： Coallier É,Kalaska JF

更新日期：2014-12-01 00:00:00

abstract：:In this article, we review a recent paper by Stevenson et al. (J Neurosci 34: 691-697, 2014). This paper illustrates the need to present different forms of stimuli in order to characterize the perceptual abilities of people with autism spectrum disorder (ASD). Furthermore, we will discuss their behavioral results and ...

journal_title：Journal of neurophysiology

authors： Chan JS,Naumer MJ

更新日期：2014-12-01 00:00:00

abstract：:We simultaneously compared the sensitivity of single primary afferent neurons supplying the glabrous skin of the hand and the psychophysical amplitude discrimination thresholds in human subjects for a set of vibrotactile stimuli delivered to the receptive field. All recorded afferents had a dynamic range narrower than...

journal_title：Journal of neurophysiology

authors： Arabzadeh E,Clifford CW,Harris JA,Mahns DA,Macefield VG,Birznieks I

更新日期：2014-11-15 00:00:00

abstract：:Low-intensity alternating electric fields applied to the scalp are capable of modulating cortical activity and brain functions, but the underlying mechanisms remain largely unknown. Here, we report two distinct components of voltage-sensitive dye signals induced by low-intensity, alternating electric fields in rodent ...

journal_title：Journal of neurophysiology

authors： Xu W,Wolff BS,Wu JY

更新日期：2014-11-15 00:00:00

abstract：:Persistent spiking in response to a discrete stimulus is considered to reflect the active maintenance of a memory for that stimulus until a behavioral response is made. This response pattern has been reported in learning paradigms that impose a temporal gap between stimulus presentation and behavioral response, includ...

journal_title：Journal of neurophysiology

authors： Siegel JJ

更新日期：2014-11-01 00:00:00

abstract：:The tail and paws in rodents are heat exchangers involved in the maintenance of core body temperature (T(core)). They are also the most widely used target organs to study acute or chronic "models" of pain. We describe the fluctuations of vasomotor tone in the tail and paws in conditions of thermal neutrality and the c...

journal_title：Journal of neurophysiology

authors： El Bitar N,Pollin B,Karroum E,Pincedé I,Mouraux A,Le Bars D

更新日期：2014-11-01 00:00:00

abstract：:Thalamocortical neurons integrate sensory and cortical activity and are regulated by input from inhibitory neurons in the thalamic reticular nucleus. Evidence suggests that during bursts of action potentials, dendritic calcium transients are seen throughout the dendritic tree of thalamocortical cells. Here, we review ...

journal_title：Journal of neurophysiology

authors： Hulme SR,Connelly WM

更新日期：2014-11-01 00:00:00

abstract：:The completion of an antisaccade (i.e., a nonstandard task) lengthens the reaction time (RT) of a subsequent prosaccade: a behavioral phenomenon termed the unidirectional prosaccade switch-cost. One explanation for the unidirectional prosaccade switch-cost is suppressing a stimulus-driven prosaccade during the precedi...

journal_title：Journal of neurophysiology

authors： Weiler J,Heath M

更新日期：2014-11-01 00:00:00

abstract：:Working memory (WM) for sensory-based information about individual objects and their locations appears to involve interactions between lateral prefrontal and sensory cortexes. The mechanisms and representations for maintenance of more abstract, nonsensory information in WM are unknown, particularly whether such active...

journal_title：Journal of neurophysiology

authors： Ikkai A,Blacker KJ,Lakshmanan BM,Ewen JB,Courtney SM

更新日期：2014-10-15 00:00:00

abstract：:Across the rostrocaudal (RC) axis of the Xenopus tadpole optic tectum exists a developmental gradient. This gradient has served as a useful model to study many aspects of synapse and dendrite maturation. To compliment these studies, we characterized how the intrinsic excitability, the ease in which a neuron can fire a...

journal_title：Journal of neurophysiology

authors： Hamodi AS,Pratt KG

更新日期：2014-10-01 00:00:00

abstract：:In this study, the juxtamembrane region of the Drosophila SNARE protein neuronal-Synaptobrevin (n-Syb) was tested for its role in synaptic transmission. A transgenic approach was used to express n-Syb mutant genes. The transgenes carried engineered point mutations that alter the amino acid sequence of the conserved tr...

journal_title：Journal of neurophysiology

authors： DeMill CM,Qiu X,Kisiel M,Bolotta A,Stewart BA

更新日期：2014-09-15 00:00:00

abstract：:Similar to most visual animals, crabs perform proper avoidance responses to objects directly approaching them. The monostratified lobula giant neurons of type 1 (MLG1) of crabs constitute an ensemble of 14-16 bilateral pairs of motion-detecting neurons projecting from the lobula (third optic neuropile) to the midbrain...

journal_title：Journal of neurophysiology

authors： Oliva D,Tomsic D

更新日期：2014-09-15 00:00:00

abstract：:Pioneering studies demonstrated that novel degrees of freedom could be controlled individually by directly encoding the firing rate of single motor cortex neurons, without regard to each neuron's role in controlling movement of the native limb. In contrast, recent brain-computer interface work has emphasized decoding ...

journal_title：Journal of neurophysiology

authors： Law AJ,Rivlis G,Schieber MH

更新日期：2014-09-15 00:00:00

abstract：:Sleep disturbances are prevalent in clinical anxiety, but it remains unclear whether they are cause and/or consequence of this condition. Fear conditioning constitutes a valid laboratory model for the acquisition of normal and pathological anxiety. To explore the relationship between disturbed sleep and anxiety in mor...

journal_title：Journal of neurophysiology

authors： Peters AC,Blechert J,Sämann PG,Eidner I,Czisch M,Spoormaker VI

更新日期：2014-09-15 00:00:00

abstract：:The exercise pressor reflex (EPR) is generated by group III and IV muscle afferents during exercise to increase cardiovascular function. Muscle contraction is triggered by ACh, which is metabolized into choline that could serve as a signal of exercise-induced activity. We demonstrate that ACh can induce current in mus...

journal_title：Journal of neurophysiology

authors： Baxter JC,Ramachandra R,Mayne DR,Elmslie KS

更新日期：2014-09-15 00:00:00

abstract：:The vestibular system operates in a push-pull fashion using signals from both labyrinths and an intricate bilateral organization. Unilateral vestibular lesions cause well-characterized motor deficits that are partially compensated over time and whose neural correlates have been traced in the mean response modulation o...

journal_title：Journal of neurophysiology

authors： Yu XJ,Thomassen JS,Dickman JD,Newlands SD,Angelaki DE

更新日期：2014-08-15 00:00:00

abstract：:Behavioral and neural findings demonstrate that animals can locate low-frequency sounds along the azimuth by detecting microsecond interaural time differences (ITDs). Information about ITDs is also available in the amplitude modulations (i.e., envelope) of high-frequency sounds. Since medial superior olivary (MSO) neu...

journal_title：Journal of neurophysiology

authors： Gai Y,Kotak VC,Sanes DH,Rinzel J

更新日期：2014-08-15 00:00:00

abstract：:The central auditory system has traditionally been divided into lemniscal and nonlemniscal pathways leading from the midbrain through the thalamus to the cortex. This view has served as an organizing principle for studying, modeling, and understanding the encoding of sound within the brain. However, there is evidence ...

journal_title：Journal of neurophysiology

authors： Straka MM,Schmitz S,Lim HH

更新日期：2014-08-15 00:00:00

abstract：:There are many theories on the purpose of neural adaptation, but evidence remains elusive. Here, we discuss the recent work by Benucci et al. (Nat Neurosci 16: 724-729, 2013), who measured for the first time the immediate effects of adaptation on the overall activity of a neuronal population. These measurements confir...

journal_title：Journal of neurophysiology

authors： Haak KV,Fast E,Baek Y,Mesik J

更新日期：2014-08-01 00:00:00

abstract：:Regulation of feeding behavior involves the integration of multiple physiological and neurological pathways that control both nutrient-seeking and consummatory behaviors. The consummatory phase of ingestion includes stereotyped oromotor movements of the tongue and jaw that are controlled through brain stem pathways. T...

journal_title：Journal of neurophysiology

authors： Nasse JS,Travers JB

更新日期：2014-08-01 00:00:00

abstract：:Electrophysiological recordings show intense neuronal firing during epileptic seizures leading to enhanced energy consumption. However, the relationship between oxygen metabolism and seizure patterns has not been well studied. Recent studies have developed fast and quantitative techniques to measure oxygen microdomain...

journal_title：Journal of neurophysiology

authors： Wei Y,Ullah G,Ingram J,Schiff SJ

更新日期：2014-07-15 00:00:00

abstract：:In the visual, auditory, and electrosensory modalities, stimuli are defined by first- and second-order attributes. The fast time-pressure signal of a sound, a first-order attribute, is important, for instance, in sound localization and pitch perception, while its slow amplitude-modulated envelope, a second-order attri...

journal_title：Journal of neurophysiology

authors： Fontaine B,MacLeod KM,Lubejko ST,Steinberg LJ,Köppl C,Peña JL

更新日期：2014-07-15 00:00:00

abstract：:Motor cortex plays a substantial role in driving movement, yet the details underlying this control remain unresolved. We analyzed the extent to which movement-related information could be extracted from single-trial motor cortical activity recorded while monkeys performed center-out reaching. Using information theoret...

journal_title：Journal of neurophysiology

authors： Golub MD,Yu BM,Schwartz AB,Chase SM

更新日期：2014-07-15 00:00:00

abstract：:The brain stem nucleus locus coeruleus (LC) is thought to modulate cortical excitability by norepinephrine (NE) release in LC forebrain targets. The effects of LC burst discharge, typically evoked by a strong excitatory input, on cortical ongoing activity are poorly understood. To address this question, we combined di...

journal_title：Journal of neurophysiology

authors： Marzo A,Totah NK,Neves RM,Logothetis NK,Eschenko O

更新日期：2014-06-15 00:00:00

abstract：:Synaptic transmission throughout most of the CNS is steeply dependent on presynaptic calcium influx through the voltage-gated calcium channels Cav2.1-Cav2.3. In addition to triggering exocytosis, this calcium influx also recruits short-term synaptic plasticity. During the complex patterns of presynaptic activity that ...

journal_title：Journal of neurophysiology

authors： Ricoy UM,Frerking ME

更新日期：2014-06-15 00:00:00

abstract：:The discovery that spontaneous fluctuations in blood oxygen level-dependent (BOLD) signals contain information about the functional organization of the brain has caused a paradigm shift in neuroimaging. It is now well established that intrinsic brain activity is organized into spatially segregated resting-state networ...

journal_title：Journal of neurophysiology

authors： Mitra A,Snyder AZ,Hacker CD,Raichle ME

更新日期：2014-06-01 00:00:00

abstract：:Self-motion generates patterns of optic flow on the retina. Neurons in the dorsal part of the medial superior temporal area (MSTd) are selective for these optic flow patterns. It has been shown that neurons in this area that are selective for expanding optic flow fields are involved in heading judgments. We wondered h...

journal_title：Journal of neurophysiology

authors： Xu H,Wallisch P,Bradley DC

更新日期：2014-06-01 00:00:00

abstract：:Adaptive processes are crucial in maintaining the accuracy of body movements and rely on error storage and processing mechanisms. Although classically studied with adaptation paradigms, evidence of these ongoing error-correction mechanisms should also be detectable in other movements. Despite this connection, current ...

journal_title：Journal of neurophysiology

authors： Wong AL,Shelhamer M

更新日期：2014-05-01 00:00:00

abstract：:Action potential initiation and conduction along peripheral axons is a dynamic process that displays pronounced activity dependence. In patients with neuropathic pain, differences in the modulation of axonal conduction velocity by activity suggest that this property may provide insight into some of the pathomechanisms...

journal_title：Journal of neurophysiology

authors： Tigerholm J,Petersson ME,Obreja O,Lampert A,Carr R,Schmelz M,Fransén E

更新日期：2014-05-01 00:00:00

abstract：:The respective roles of ventral and dorsal cortical processing streams are still under discussion in both vision and audition. We characterized neural responses in the caudal auditory belt cortex, an early dorsal stream region of the macaque. We found fast neural responses with elevated temporal precision as well as n...

journal_title：Journal of neurophysiology

authors： Kusmierek P,Rauschecker JP

更新日期：2014-04-01 00:00:00